Boss rush unlocks ranking – The Binding of Isaac: Rebirth

Boss rush unlocks ranking – The Binding of Isaac: Rebirth 19 - steamclue.com
Boss rush unlocks ranking – The Binding of Isaac: Rebirth 19 - steamclue.com

Heya fellow isaac players, in this guide i’ll give a ranking on boss rush unlocks for non-tainted characters, with a difficulty rating and a value rating for how good the unlock is.
 
do note, this is a personal opinion, so if one of y’all thinks an unlock is better than i give it credit for, please do enlighten me as to why you think so!
 
 

Isaac: Isaac’s Head.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Isaac: Isaac's Head. - 1B4578888Difficulty: 4/10
 
isaac doesn’t really have issues with boss rush, especially if D6 is unlocked.
 
Unlock rating: C
 
useful early on due to it’s piercing, but the competition for the trinket slot is typically better
 
 
 

Maggy: Maggy’s bow.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Maggy: Maggy's bow. - ECC890FDC Difficulty: 5/10
 
yum heart and red health makes surviving easier, but DPS can be an issue.
 
Unlock value: A
 
varies from character to character, but is typically pretty damn decent. completely broken when playing as T. maggy.
 
 
 

Cain: Cain’s other eye.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Cain: Cain's other eye. - 4FCA36531Difficulty: 5/10
 
basically the opposite of maggy, good DPS, but questionable survivability.
 
Unlock value: D
 
a waste of a treasure pool item in my opinion, nonexistant DPS and uncontrollable movement. at least peeper gives a damage up!
 
 
 

Judas: Judas’ shadow.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Judas: Judas' shadow. - 1A40472D0Difficulty: 2/10
 
book of belial OP, nuff said
 
Unlock value: A
 
a revive item that makes you judas with a 2X damage multiplier? sign me UP!
 
 
 

???: ???’s only friend.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - ???: ???'s only friend. - 82FD2F4E8Difficulty: 7/10
 
??? having only soul hearts hurts a LOT here, coz most bosses will only drop red health.
 
Unlock value: C
 
nothing amazing, but i’d take it over a godamn stat upgrade. also counts for beelzebub so that’s nice.
 
 
 

Eve: Eve’s mascara.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Eve: Eve's mascara. - CEFA98DD1Difficulty: 5/10
 
depends on whether WoB is being relied on, and even then, it shouldn’t be too hard.
 
Unlock value: A
 
kind of a controversial unlock last time I checked, but i love it! again i must say, i love me a damage multiplier!
 
 
 

Samson: Samson’s chains.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Samson: Samson's chains. - BB9200DC9OK first off what the hell is up with the boss rush unlocks having character’s names? this is kinda weird if you ask me.
 
Difficulty: 4/10
 
the bloody lust stacks, they are ridiculous. if you don’t end off on like +8 damage, you probably deserve an award!
 
Unlock value: B
 
free tinted rocks, skulls, pots and more! kinda awkward to use, but never a bad take.
 
 
 

Azazel: The nail.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Azazel: The nail. - 734092536Difficulty: 3/10
 
Azazel is OP early game, and this is no exception. only potential issues could be death or bloat (f@ck bloat).
 
Unlock value: C
 
a bunch of random and awkward 1-room buffs piled into one item, plus HALF a black heart. this feels like a filler item if you ask me.
 
 
 

Lazarus: MISSINGNO.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Lazarus: MISSINGNO. - 079F11A26Difficulty: 5/10
 
only putting lazarus higher than isaac coz it could be hard if you have became lazarus risen prior to entering (voluntarily or not!)
 
Unlock value: E
 
GOD THIS ITEM SUX! just let me keep my build for 5 MINUTES!
 
 
 

Eden: UNDEFINED.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Eden: UNDEFINED. - 2EABDEB74Difficulty: 4/10
 
depends heavily on the start of the run, but shouldn’t be too hard.
 
Unlock value: B
 
easy access to IAMERROR rooms, what’s not to like?
 
 
 

The Lost: D100.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - The Lost: D100. - 239A5A853Difficulty: 8/10
 
PAIN. LOTS OF PAIN.
 
Unlock value: C
 
for when you want to tell your current run to go screw itself!
 
 
 

Lilith: Immaculate conception.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Lilith: Immaculate conception. - 56AA306B7Difficulty: 6/10
 
rock layouts can be a nightmare, but only if you don’t have spectral.
 
Unlock value: A
 
it gives holy water, relic and 2 orbitals. better to get earlier in a run rather than later.
 
 
 

Keeper: Sticky nickels.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Keeper: Sticky nickels. - AF2DC3C19Difficulty: 7/10
 
Keeper struggles coz his survivability is horrid. not complaining about wooden nickel, but it’s a tad inconsistent.
 
Unlock value: F
 
WHY IS THIS AN UNLOCK? IT ACTIVELY MAKES THE GAME WORSE!
 
 
 

Apollyon: Locust of conquest.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Apollyon: Locust of conquest. - 96A9872ABDifficulty: 5/10
 
isaac but with void, next!
 
Unlock value: B
 
definitely a better trinket than isaac’s head, but again, the competition can beat it out just barely.
 
 
 

The forgotten: Divorce papers.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - The forgotten: Divorce papers. - 529CDDA45Difficulty: 4/10
 
the dual healthbars allow for variation in playstyle and the bone club can take out bas*ment bosses real fast.
 
Unlock value: B
 
it’s a boss pool unlock, but a damn good one at that.
 
 
 

Bethany: Beth’s faith.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Bethany: Beth's faith. - 098C1C014Difficulty: 3/10
 
BoV is just as good for boss rush as BoB. just spam out wisps and take basically no damage.
 
Unlock value: C
 
same boat as isaac’s head, but the wisps can be useful all the way until delirium, also wtf the names are back!
 
 
 

Jacob and Esau: Rock Bottom.

Boss rush unlocks ranking - The Binding of Isaac: Rebirth - Jacob and Esau: Rock Bottom. - 9FE55B2BADifficulty: 8/10
 
JandE is painful to play as, especially here due to the onslaught of bosses with little health to boot.
 
Unlock Value: S
 
yes, i know rock bottom is overhyped to some degree, but that doesn’t mean it isn’t an absolutely great item!
 
 
 

Conclusion.

overall, i think boss rush is one of the easier completion marks (that gives a consequential unlock that is!), but the unlocks are very hit and miss.
 
 
I hope this guide was enlightening, and if you have an opinion of your own, please do let me know!
 
 

Written by M1DKN1GH7

 
 
I hope you enjoy the Boss rush unlocks ranking – The Binding of Isaac: Rebirth guide. This is all for now! If you have something to add to this guide or forget to add some information, please let us know via comment! We check each comment manually!
 


Be the first to comment

Leave a Reply

Your email address will not be published.


*